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  • Clarie Ds 250mg/5ml 50ml

Clarie Ds 250mg/5ml 50ml

kes1,160
Description
Clarithromycin 250 mg/5 ml suspension is indicated in adults, adolescents and children, 6 months to 12 years, for the treatment of the following acute and chronic infections, when caused by clarithromycin susceptible organisms.
• Infections of the upper respiratory tract such as tonsillitis/pharyngitis, as an alternative when beta lactam antibiotics are not appropriate.
• Acute otitis media in children.
• Infections of the lower respiratory tract such as community acquired pneumonia.
• Sinusitis and acute exacerbation of chronic bronchitis in adults and adolescents over 12 years of age.
• Skin infections and soft tissue infections of mild to moderate severity.
In appropriate combination with antibacterial therapeutic regimens and an appropriate ulcer healing medicinal product for the eradication of Helicobacter pylori in adult patients with H. pylori associated ulcers.
How to use
Adults and adolescents: Standard dosage: The usual dose is 250 mg twice daily.
High dosage treatment (severe infections): The usual dose may be increased to 500 mg twice daily in severe infections.
Elimination of Helicobacter pylori in adults: In patients with gastro-duodenal ulcers due to H. pylori infection clarithromycin as part of the first line triple therapy is given in a dosage of 500 mg twice daily. The national recommendations for Helicobacter pylori eradication have to be considered.
Dosage in patients with renal impairment: The maximum recommended dosages should be reduced proportionately to renal impairment. At creatinine clearance rate of less than 30 ml/min, the dosage should be halved to 250 mg daily or in the most severe infections to 250 mg twice daily. The duration of treatment should not exceed 14 days in these patients.
Precautions
Contraindications: Clarithromycin is contraindicated in patients with known hypersensitivity to the active substance, other macrolide antibiotic drugs or to any of the excipients listed. Concomitant administration of clarithromycin and any of the following drugs is contraindicated: astemizole, cisapride, pimozide and terfenadine, as this may result in QT prolongation and cardiac arrhythmias, including ventricular tachycardia, ventricular fibrillation and Torsade de Pointes. Concomitant administration with ticagrelor or ranolazine is contraindicated. Concomitant administration of clarithromycin and ergotamine or dihydroergotamine is contraindicated, as this may result in ergot toxicity.