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Inosita Plus tablet contains Sitagliptin and Metformin which belongs to Biguanide/Dipeptidyl peptidase-4 inhibitors. Metformin is an oral medication that lowers blood glucose by increasing the sensitivity of liver, muscle, fat, and other tissues to the effects of insulin. Increasing the sensitivity of tissues to insulin causes more glucose to be removed from blood and thereby reduces the level of glucose in the blood. In scientific studies, metformin reduced the complications of diabetes such as heart disease, blindness and kidney disease. Sitagliptin is an oral drug that reduces blood glucose levels in patients with type 2 diabetes.
Give twice daily with meals, with gradual dose escalation, to reduce the gastrointestinal effects due to metformin.
Lactic acidosis is a serious side effect of metformin that occurs in one out of every 30,000 patients and is fatal in 50% of cases. The symptoms of lactic acidosis are weakness, trouble breathing, abnormal heartbeats, unusual muscle pain, stomach discomfort, light-headedness and feeling cold. Patients at risk for lactic acidosis include those with reduced function of the kidneys or liver, congestive heart failure, severe acute illnesses, and dehydration. Inosita should be discontinued immediately if lactic acidosis is suspected. The following information is an educational aid only. It is not indicated as medical advice or alternative treatment. Consult your Doctor on safety and effectiveness.
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