iOS
Android
Facebook
WhatsApp
Twitter
Presartan is a synthetic oral angiotensin-II receptor (type AT1) antagonist. Angiotensin II, a potent vasoconstrictor, is the primary active hormone of the renin/angiotensin system and an important determinant of the pathophysiology of hypertension. Angiotensin II binds to the AT1Â receptor found in many tissues (e.g. vascular smooth muscle, adrenal gland, kidneys and the heart) and elicits several important biological actions, including vasoconstriction and the release of aldosterone. Angiotensin II also stimulates smooth muscle cell proliferation. Â Treatment of essential hypertension in adults and in children and adolescents 6-18 years of age.
Losartan potassium 50 mg
The usual starting and maintenance dose is 50 mg once daily for most patients. The maximal antihypertensive effect is attained 3-6 weeks after initiation of therapy. Some patients may receive an additional benefit by increasing the dose to 100 mg once daily (in the morning). Losartan may be administered with other antihypertensive agents, especially with diuretics (e.g. hydrochlorothiazide).
Hypersensitivity to the active substance or to any of the excipients listed in sections 4.4 and 6.1. • 2nd and 3rd trimester of pregnancy (see sections 4.4 and 4.6). • Severe hepatic impairment. • The concomitant use of Losartan potassium with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 ml/min/1.73 m2)Â
KES 760.00
Delivery within 4 hours on all orders placed between 8:00 AM & 8:00 PM
