Claritek (Clarithromycin) is a semi-synthetic macrolide antibiotic. Clarithromycin exerts its anti-bacterial action by binding to the 50s ribosomal sub-unit of susceptible bacteria and suppresses protein synthesis. It is highlypotent against a wide variety of aerobic and anaerobic gram-positive and gram-negative organisms. Indications: For treatment of infections due to susceptible organisms. Such infections include: -Lower respiratory tract infections (e.g., bronchitis, pneumonia). -Upper respiratory tract infections (e.g. pharyngitis, sinusitis, tonsillitis). -Acute otitis media in children. -Skin and soft tissue infections (e.g., folliculitis, cellulitis, erysipelas, impetigo, abscesses). -Disseminated or localized mycobacterial infections due to MAC. -To eradicate Helicobacter pylori in treatment regimens for peptic ulcer disease. -To prevent disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection. -As an alternative treatment to penicillins for prophylaxis of endocarditis.
Adults: The usual recommended dosage of CLARITEK (Clarithromycin) is 250 mg tablet twice daily. In more severe infections the dosage can be increased to 500 mg twice daily. The usual duration of therapy is 6 to 14 days.
CONTRAINDICATIONS: -Clarithromycin is contraindicated in patients with known hypersensitivity to the active substance, other macrolide antibiotics or to any of the excipients. -Concomitant administration of clarithromycin with any of the following medicines is contraindicated: astemizole, cisapride, pimozide and terfenadine. -Concomitant administration of Clarithromycin with ergot derivatives is contraindicated. The following information is an educational aid only. It is not indicated as medical advice or treatment. Consult your Doctor on safety and effectiveness.
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