Do not use in severe kidney disease, diabetic ketoacidosis, severe dehydration, serious infection or heavy alcohol use. These raise the risk of rare but serious lactic acidosis (rapid breathing, severe weakness, unusual muscle pain. Seek urgent care). Kidney function should be checked periodically; metformin may be paused around contrast-dye scans or major surgery. Long-term use can lower vitamin B12. Early nausea, metallic taste or loose stools usually settle. Take with food. Tell your doctor if pregnant, planning pregnancy or breastfeeding. Store below 30°C. This product information is for general guidance only and does not replace professional medical advice. Always consult a qualified healthcare provider before starting any new medication or supplement. Keep all medicines out of reach of children.