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Irnazin is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Irnazin is used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old. Irnazin is also used to treat itching and swelling caused by chronic urticaria (hives) in adults and children who are at least 6 months old. Irnazin 5mg is used for symptomatic relief of allergic conditions such as allergic rhinitis, conjuctivitis and chronic urticaria.
Adults And Children 12 Years Of Age and Older: The recommended dose of Irnazin is 5 mg (1 tablet) once daily in the evening. Some patients may be adequately controlled by 2.5 mg (½ tablet once daily in the evening.) Children 6 To 11 Years Of Age: The recommended dose of Irnazin is 2.5 mg (½ tablet) once daily in the evening. The 2.5 mg dose should not be exceeded because the systemic exposure with 5 mg is approximately twice that of adults. Dose Adjustment For Renal And Hepatic Impairment In adults and children 12 years of age and older with: -Mild renal impairment (creatinine clearance [CLCR] = 50-80 mL/min): a dose of 2.5 mg once daily is recommended; -Moderate renal impairment (CLCR = 30-50 mL/min): a dose of 2.5 mg once every other day is recommended; -Severe renal impairment (CLCR = 10-30 mL/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended; -End-stage renal disease patients (CLCR < 10 mL/min) and patients undergoing hemodialysis should not receive Irnazin. No dose adjustment is needed in patients with solely hepatic impairment. In patients with both hepatic impairment and renal impairment, adjustment of the dose is recommended.
You should not use this medication if you are allergic to Irnazin or cetrizine (Zyrtec). Do not take Irnazin if you have end-stage kidney disease or if you are on dialysis. Any child younger than 12 years old with kidney disease should not take Irnazin. Before taking Irnazin, tell your doctor if you have liver disease, kidney disease, or gallbladder problems. It is very important not to give a child more than the prescribed dose of this medication. A child's body absorbs twice as much of the same dose size of Irnazin as an adult's body. Call your doctor if your symptoms do not improve, if they get worse, or if you also have a fever. The information provided is for educational aid only. It is not indicated as medical advice or treatment. Please consult your physician for safe use and effectiveness.
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