Must NOT be used during pregnancy. Isotretinoin causes severe birth defects. Women of childbearing age must use effective contraception for at least 1 month before, during and for 1 month after treatment, with pregnancy testing as directed. Do not breastfeed or donate blood during and for 1 month after treatment. Expect dry lips, skin and eyes. Use lip balm and moisturiser; avoid waxing and strong sun exposure. Report mood changes, depression, severe headaches, stomach pain or vision changes promptly. Avoid vitamin A supplements and tetracycline antibiotics. Blood lipid and liver monitoring is required. Store below 25°C. This product information is for general guidance only and does not replace professional medical advice. Always consult a qualified healthcare provider before starting any new medication or supplement. Keep all medicines out of reach of children.